Oxlade-Chamberlain scored one in each half, before late goals from Sadio Mane and Mohamed Salah sealed the win, and Stephen Odey netted a deserved reply for an entertaining Genk side.
The Liverpool midfielder was starting his first game in the competition for 18 months as Jurgen Klopp’s side looked to end the strange run of away struggles in the group stages of a tournament they won last season in their second straight final.
And it didn’t take the former Arsenal man long to make an impact as he fired a low drive into the bottom corner after just a couple of minutes of the game had gone in Belgium.
The hosts really troubled Liverpool on the break though, even having a goal ruled out by VAR for offside, and it was not until Oxlade-Chamberlain curled in a fantastic second with the outside of his right foot that the points finally looked safely tucked away.
Mane dinked in a wonderful third goal after a flowing move involving all three of Liverpool’s front men, Roberto Firmino supplying Salah who then showed a expert touch to put through Mane.
Salah then coolly slotted home a fourth but Genk deserved a goal for all their endeavour and they got one just before the end when Dejan Lovren was robbed in possession and Odey eventually turned a fired beyond Alisson.
Group E as it stands
Liverpool now sit in second place in Group E behind Napoli after the Italian side emerged with a 3-2 win from their visit to Red Bull Salzburg in the other game of the night.
The two fixtures on the night are reversed for the next matchday as Genk visit Liverpool and Salzburg travel to Naples, before what could then be a crucial meeting between Liverpool and Napoli at Anfield.
Genk 1-4 Liverpool Opta stats
- Liverpool have won 25 of their last 30 matches in all competitions (W25 D3 L2), with that run including seven victories in the Champions League.
- Genk have now played more matches than any other team in the history of the European Cup/Champions League without winning a game (15 – W0 D8 L7).
- Liverpool became the fourth English team to score 200 goals in the Champions League, after Arsenal (281), Chelsea (269) and Manchester United (373).
- This was the second consecutive Champions League match in which a Liverpool player assisted a goal on his birthday – Roberto Firmino did so against FC Red Bull Salzburg and Fabinho tonight against Genk.
- Genk conceded more than once in a home Champions League game for the first time, with this only their second home defeat in the competition (also 1-0 against Roma in October 2002).
- Four of Alex Oxlade-Chamberlain’s seven goals for Liverpool in all competitions have been scored from outside the box.
- Since the start of the 2017-18 season, Liverpool’s Roberto Firmino has more assists in the Champions League than any other player (11).